A four-year-old child took about 250 packets of heroin to her nursery and began passing them out, believing them to be chocolate, Delaware police say.
Police say the child unknowingly brought the drugs to the centre when her mother gave her a different bag to take to nursery.
The girl's mother, Ashley Tull, 30, has been charged with child endangerment and a drugs charge.
Her sister told the Associated Press she had no idea the drugs were inside.
Alicia Tull said her sister does not use or deal drugs and that she was taken advantage of by an individual who stored the drugs in her home without her knowledge.
Delaware Police Master Cpl Gary Fournier told the Delaware News Journal newspaper the "investigation is continuing and more charges are forthcoming" but would not say whose heroin it was.
Several children who received the packets went to hospital as a precaution, police said, but none of the packets was opened.
In total, the bags held nearly 4g (0.14 ounce). Each packet was labelled "Slam".
Ms Tull has been released on a $6,000 (£3,700) bond has been ordered not to have any contact with her children, ages 11 to four, who are in the custody of a relative, Delaware State Police said.
美国特拉华州（Delaware）警方说：“一个四岁的孩子携带了约250小包的海洛因到幼儿园后开始分发，孩子们以为这些是糖果。”
警方说孩子的母亲给了孩子一个不同的背包，孩子不知不觉就把毒品带到了日托中心。
女孩的母亲艾希礼（Ashley)30岁，已被指控危害儿童和吸毒。
艾希礼的姐姐告诉美联社记者她不知道背包中藏有毒品。
艾丽西亚（Alicia）说她妹妹没有吸毒或进行毒品交易，她只是帮他人保存物品从而获利，而有些人把毒品藏在她家，她毫不知情。
特立华州警署负责人（Delaware Police Master Cpl)加里福尼尔（Gary Fournier）告诉特拉华资讯报（Delaware News Journal nespaper)：“调查还在继续，也将会有更多指控”，但可能不会指明海洛因是谁的。
警方说一些收到小包海洛因的孩子为了确保无恙便去医院，但是这些海洛因包装都还是密封的。
这些海洛因重总计约4克。每个小包都被贴上了“Slam”糖果的标签。
图勒女士已被释放，她交了6000美金作担保，并且被禁止接近她的孩子们。她的孩子们4到11岁，目前由一个亲戚监护。
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