Milito scored in the 40th minute at Stadio Olimpico, carrying the ball past three defenders before hitting a powerful shot, boosting its chances of becoming the first Italian club to win a treble.
Milito also scored once and set up two goals in Inter's 3-1 winover Barcelona in the opening leg of the Champions League semifinals.
Inter Milan's Wesley Sneijder holds up the trophy after winning the Italian Cup final soccer match against AS Roma at the Olympic stadium in Rome May 5, 2010. This is Inter Milan's sixth Italian Cup triumph. Inter Milan won 1-0.
Inter faces Bayern Munich for the Champions League title on May22 in Madrid and holds a two-point lead over Roma with two games remaining in Serie A.